https://www.ceesdekker.net Secrets
https://www.ceesdekker.net Secrets
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‘Certainly, which is about right. I seek out a Actual physical knowledge of Organic systems in the base-up way. I think you might distinguish a few lines of analysis in my team in the meanwhile. The main considerations chromosome framework: How does one get yourself a metre-very long DNA polymer folded and organised in such a microscopic cell? We've got formulated visualisation techniques that permit us to review how, such as, SMC proteins loop DNA (video on Youtube) to be able to Create up chromosomes.
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Dynamics of initiation, termination and reinitiation of DNA translocation from the motor protein EcoR124I
2007, 1st real-time detection of strand exchange in homologous recombination by RecA; discovery of the low persistence length of finishes of microtubules; and fixed the mechanism of biosensing with carbon nanotubes
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent design in 2005. (nl)
Our study ranges through the biophysics of DNA to artificial cells and outside of. Make sure you have a look underneath for the spectrum of our present-day projects.
What distinguishes biology from chemistry is the fact these elements alongside one another make up a residing system. The key of said lifetime, I think, lies during the interactions, the interplay of All those molecules. The big dilemma in regards to the origin of life remains to be unanswered. How did we at any time evolve from straightforward molecules into your incredibly complex programs we see now? We have no idea. I would like to operate on these kinds of major, open issues.’
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‘The fantastically subtle way in which elements in mother nature purpose never ever ceases to amaze cees dekker me. If we fix the puzzle of how existence came into remaining, I be expecting that my amazement with the complexity of creation will have amplified and with it my awe for the greatness of your Creator.’
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2006, 1st demonstration of molecular sorting inside a lab over a chip applying biomotors; discovery of nanobubbles in strong-condition nanopores; and initially estimate of electrokinetic Power conversion in the nanofluidic channel
2005, discovery from the system of DNA uncoiling by topoisomerase enzymes; discovery of lengthy-array conformational alterations in Mre11/DNA maintenance complexes; and initial force measurements on the DNA molecule inside of a nanopore
Ultimately, I will briefly sketch a few of our Tips to investigate the creating of synthetic cells, particularly our initial actions to establish artificial mobile division.